醫學微生物學和免疫學涵蓋了傳染病及其宿主之間相互關系的所有方面。主要內容包括微生物和病毒的發病機制以及免疫宿主對感染的反應。該雜志還出版了其他微生物學領域的信息，包括真菌學和寄生蟲學。

Medical Microbiology and Immunology covers all aspects of the interrelationship between infectious agents and their hosts. Among the major topics covered are microbial and viral pathogenesis and the immunological host response to infections. The journal also publishes information from other fields of microbiology, including mycology and parasitology.